Endocrine Abstracts

Introduction: Diabetic neuropathy is the most common cause of neuropathy worldwide and is known to affect approximately half of all diabetic patients. It significantly impairs the quality of life of patients.Aim of the study: To establish the predictive factors of distal symmetric polyneuropathy (DSPN) in diabetic patients.Methods: This is a descriptive cross-sectional study including 116 patients. The diagnosis of PNDS was establi...

Introduction: The prevalence of diabetes in the world population is increasing day by day so that its frequency reaches epidemic proportions. As a result, the complications of diabetes are becoming more and more frequent. Diabetic neuropathy, the most common complication which affect up to half of the patients.Purpose of the study: To establish the prevalence of distal symmetrical polyneuropathy (DSPN) in diabetic patients and demonstrate the importance ...

Objective: to analyze the dietary and metabolic factors predictive of the occurrence of pancreatitis in patients with type 1 diabetes mellitus (T1DM).Patients and Methods: Analytical case-control study of 31 T1DM patients separated into two subgroups: G1 (n=10): T1DM cases with pancreatitis. G2 (n=21): T1DM controls without pancreatitis.Results: The age at diagnosis of T1DM was comparable between the two groups. A...

Background and aim: Acromegaly is a rare condition caused by an excessive secretion of growth hormone (GH) and insulin-like growth factor1 (IGF-1), which are responsible for exaggerated somatic growth, cardiometabolic disturbances and an increased neoplastic risk. This study aims to assess the tumorigenic potential of GH excessive secretion.Patients and Methods: We conducted a retrospective study (1997-2020) at the Endocrinology department of Hedi Chaker...

Background and aim: Acromegaly is a rare condition caused by an excessive secretion of growth hormone (GH) and insulin-like growth factor1 (IGF-1), which are responsible for exaggerated somatic growth and cardiometabolic disturbances. This study aims to determine the prevalence of obesity in patients with acromegalyPatients and Methods : We conducted a retrospective study (1997-2020) at the Endocrinology department of Hedi Chaker University Hospital, Sfa...

IntroductionThe association of type 1 diabetes with other autoimmune diseases is well known due to a common genetic terrain of varied clinical expressions. However, the occurrence of systemic diseases in diabetic patient, whatever the type of diabetes, is poorly studied. The objective of this study is to describe autoimmune and inflammatory diseases associated with diabetes.Materials and methodsIt ’ s a ...

Introduction: Addison disease is associated with high risk of fractures and low bone mineral density. Causes are complex, including supraphysiologic glucocorticoid replacement therapy and concomitant autoimmune disorders. The aim of our study is to assess the influence of glucorticoid replacement therapy on bone mineral density in patients with Addison disease.Patients and methods: Descriptive and analytical cross- sectional study including 50 patients w...

Introduction: Distal and symmetrical peripheral polyneuropathy is the most frequent type of diabetic neuropathy. Its painful form (PDN) is the most common cause of non-traumatic neuropathic pain and can place a heavy burden on patients’ lives. Despite the major impact that it can have on the quality of life, PDN is generally underdiagnosed because of a large interindividual variability of symptoms and in the absence of well-established diagnostic criteria.<p class="ab...

Background and Aims: Lower urinary tract (LUT) dysfunctions are highly prevalent, especially in women. Diabetes is a well-established risk factor for developing LUT symptoms. Several studies suggest that a high body mass index (BMI) may worsen the urinary discomfort in patients with type 2 diabetes (T2DM). The current survey aims to investigate the relationship between obesity and LUT dysfunctions in patients with T2DM.Patients and Method: We conducted a...

Background and Aims: Several studies have pointed a significant relationship between diabetic complications, glycemic imbalance, and the onset of lower urinary tract dysfunction (LUTD) in this population. The current survey aims to assess the clinical and biochemical characteristics related to glycemic control in patients with type 2 diabetes presenting with symptoms of LUTD.Patients and Method: We conducted a comparative cross-sectional study that inclu...